Super-resolution imaging
Sometimes it's just more fun to go super-res.
Dynein, dynein
Axonemal dynein are molecular motors that make cilia and flagella move. They have not previously been associated with primary cilia. We show that they are robustly expressed in human and mouse islet cilia and centrioles.
Below: axonemal dynein (green), acetylated tubulin (red)
DNAI1 expression in primary cilia
human islet, airyscan
DNAI1 along cilia microtubules
mouse islet, nsparc
A ring of DNAI1 in cilia
human islet, nsparc
DNAH11 in centrioles
human islet, nsparc