Primary Cilia in Islet Biology
In the Hughes Lab, we investigate primary cilia to understand how compartmentalized signals within these organelles shape whole-cell function and influence human health. We are particularly interested in how ciliary dysfunction contributes to diseases beyond the classical ciliopathies.
Research Questions
Join our team and help shape future questions in islet cilia biology.
Contact: jing.hughes@yale.edu
Sensory Organelle
What does the islet cilium sense, and why does it matter for metabolism?
How do ciliary GPCRs generate signals that control the entire cell?
Signaling Hub
Cilia Dynamics
How do primary cilia move and power their motion, and what purpose does it serve?
Gallery
Explore our research images on pancreatic islet primary cilia.
Contact Us
Reach out to our islet biology lab for inquiries about cilia regulation and islet cell research.
Connect
2037372939
Inquire
jing.hughes@yale.edu